Facing multiple IVF failures can be emotionally and physically challenging, leaving couples feeling hopeless. However, recurrent IVF failure does not mean the end of your fertility journey. With the right medical evaluation and personalized treatment, many couples can still achieve successful pregnancy.

Dr. Sravya Buggana specializes in identifying the underlying causes of failed IVF cycles and providing advanced fertility treatments to improve success rates.

What is Recurrent IVF Failure?

Recurrent IVF failure is defined as two or more unsuccessful IVF cycles despite the transfer of good-quality embryos. Several factors can contribute to repeated failures, and a detailed evaluation is crucial to determining the next steps.

Causes of Recurrent IVF Failure

✔ Poor Embryo Quality – Even if embryos appear healthy under a microscope, genetic abnormalities can affect implantation.
✔ Uterine Receptivity Issues – Endometrial lining problems, polyps, fibroids, or inflammation can prevent implantation.
✔ Genetic Factors – Chromosomal abnormalities in eggs, sperm, or embryos may lead to failed pregnancies.
✔ Immune System Disorders – Autoimmune reactions can impact embryo implantation.
✔ Poor Egg or Sperm Quality – Advanced maternal age, poor ovarian response, or sperm DNA fragmentation can reduce success rates.
✔ Hormonal Imbalances – Thyroid disorders, high prolactin levels, or progesterone deficiencies can disrupt embryo implantation.
✔ Blood Clotting Disorders – Conditions like thrombophilia can reduce blood flow to the uterus, affecting embryo attachment.

Diagnostic Tests for Recurrent IVF Failure

To determine the root cause, Dr. Sravya Buggana may recommend:

• Comprehensive Embryo Testing (PGT-A, PGT-M) – Checks for genetic abnormalities.
• Endometrial Receptivity Analysis (ERA) – Identifies the best time for embryo transfer.
• Hysteroscopy & Ultrasound – Detects uterine abnormalities like polyps, fibroids, or adhesions.
• Immune System Testing – Assesses autoimmunity or inflammation affecting implantation.
• Sperm DNA Fragmentation Test – Evaluates sperm health beyond standard semen analysis.
• Blood Clotting & Hormonal Tests – Checks for conditions affecting embryo implantation.

Treatment Approaches for Recurrent IVF Failure

Dr. Sravya Buggana tailors treatment plans based on diagnostic findings. Common strategies include:

✔ Preimplantation Genetic Testing (PGT-A, PGT-M) – Ensures only genetically healthy embryos are transferred.
✔ Endometrial Receptivity Testing (ERA) – Determines the optimal timing for embryo transfer.
✔ Hysteroscopic Surgery – Removes uterine polyps, fibroids, or adhesions that may affect implantation.
✔ Immune Therapy – Treats autoimmune conditions that interfere with embryo attachment.
✔ Personalized Medication Protocols – Adjusts hormonal support for better embryo implantation.
✔ Sperm Selection Techniques – IMSI, PICSI, and DNA fragmentation testing improve sperm quality.
✔ Frozen Embryo Transfer (FET) – Allows better endometrial preparation before implantation.
✔ Lifestyle & Nutritional Support – Enhances fertility with dietary and lifestyle changes.

Lifestyle Tips to Improve IVF Success

✔ Maintain a Healthy Diet – Increase intake of antioxidants, vitamins, and fertility-boosting nutrients.
✔ Manage Stress – Practice yoga, meditation, or therapy for emotional well-being.
✔ Avoid Smoking & Alcohol – Reduces oxidative stress affecting egg and sperm quality.
✔ Optimize Weight & Exercise – Maintain a healthy BMI for hormonal balance.
✔ Follow Doctor’s Advice – Adhere to prescribed medications and protocols.